RPM – A Breakthrough Pre-Workout formula in a class by itself: the world’s first Anabolic-Cognitive Energy System Enhancer (A-CESE): (Anabolic + Cognitive Psy-Stimulant)
RPM delivers:
 Explosive energy without the jitters
 Intense mental focus
 Measurable strength increases
 Unparalleled pumps
 Suppressed estrogen
 Increased testosterone
 Thermogenic fat metabolization
RPM mimics the mechanisms and effects of experimental pharmaceutical-grade compounds called SARMs (Selective Androgen Receptor Modulators) which are being touted as a future class of drugs that will effectively replace traditional anabolic preparations due to their absence of negative side-effects.
All of this is accomplished using 100% safe herbal preparations in its ingredient profile.
Results are noticed from the very first dose, plus RPM provides positive cumulative effects with continued use.
Goals.
We all have them. But what truly is a goal ?
Webster’s dictionary defines a goal as:
The end toward which effort is directed
The terminal point of a race.
But when it comes to fitness and bodybuilding goals, these definitions only tell part of the story. Yes, we want to get there. But we want to get there FAST. Whether your goal is losing a few pounds, increasing strength, or bursting through a new plateau, we all want to race to our “personal finish lines” as fast as possible. Unfortunately, conflicting goals in our lives often get in the way of our fitness goals and we get sidelined from the race. Therefore we seek out products to help improve our chances of reaching our goals more quickly and easily. Unfortunately, all too often hard-earned dollars are spent on products that make great claims, only for us to be disappointed and no closer to our goals than when we started. Sound familiar?
Applied Nutriceuticals has the answer to putting you back in the driver’s seat and speeding towards your goal faster that you ever thought possible!  That product is RPM™ a Phyto-Chemical Selective Androgen Receptor Modulator (PSARM). RPM is a breakthrough formulation that provides explosive energy, uncanny mental focus, amazing strength increases, insane pumps, suppressed estrogen, increased testosterone…all while incinerating fat! Best of all, these results are noticed from the very first dose! RPM gives the best of both worlds…instant gratification coupled with long-term results!
Let’s look at each benefit that this super-charged formula provides……………
Explosive Energy
Not since the days of Ephedra has there been such a high octane formula available to rev up your workouts. Within 1 hour of the very first dose you will feel the blood flowing like never before.  No longer are there any feelings of fatigue from a busy day or a poor night’s sleep.
Uncanny Mental Focus
As you begin your warm up, any nagging thoughts cluttering your mind give way to a more purposeful, focused state of mind that allows you to concentrate on the task at hand; your workout. As your energy increases the body and mind become one allowing you to focus on your training like never before. RPM’s unique blend of cognitive and mood enhancers give you drive like no other product that helps improve every aspect of your life.
Amazing Strength Increases
From the very first dose you will notice the RPM is much more than just another pre-workout energy formula. RPM’s unique blend of compounds combine potent testosterone boosters that will allow you to achieve your goals of size and strength faster than you ever thought possible! RPM’s amazing ingredient blueprint applies new scientific theories regarding SARMs (Selective Androgen Receptor Modulators) in a completely unique way; pushing RPM’s effectiveness past any other conventional testosterone booster. Building lean hard muscle tissue has never been this easy.
Mind-blowing pumps
Ready for insane volume? RPM will give you pumps like never before. No, we’re not referring to the same old half-hearted pumps that quickly go away and leave you feeling deflated. We are talking true fullness and volume. RPM provides acute vasodilation action by increasing Nitric oxide thru PDE5 inhibition, leading to a stronger and much more forceful contraction. In short, RPM has a longer lasting more potent NO pump then you have ever felt before.
Increased Density and Hardness
When you work hard, you want it to show and to look our best.  RPM dramatically hardens the look of your physique by reducing aromatase and estradiol.   The end result is a denser, harder look with reduced water retention. Now you can finally show off the results of hours in the gym and display the lean muscle you have worked so hard for.
Incinerates FAT
RPM’s revolutionary formula is also a very potent fat burner. The thermogenic qualities of RPM are reminiscent of the old Ephedra days, without having to stack it with anything else to make it work!
Instant gratification. Long term gains. Intensity. Strength. Energy. Focus. Drive. Pump. Fat Burning. It’s all here. Your personal checkered flag has never been so close. It’s time to get in the race
The Iingredients from RPM :
Icariin is one of the key constituents in the P-SARM Synthase AI component of RPM. Several studies have shown that icariin competes with glucocorticoids for receptor sites in a manner similar to testosterone and improves the testosterone / cortisol ratio. This is caused by several different mechanisms of action; the aforementioned competition with glucocorticoids, via increased testosterone production which is accomplished through increased cAMP (cyclic AMP, a second messenger important in hormone signaling) levels, increased luteininzing hormone (LH) levels, the mimicry of testosterone in spermatogenesis, and decreased prolactin levels.  It has been shown that icariin blocks glucocorticoids from binding to cortisol receptors, hence blocking the actions of cortisol.  This alone creates an anabolic effect by positively skewing the testosterone / cortisol ratio, which is a trigger for greater protein synthesis, increased aggression, and intensified muscle contractions.
Users of RPM report huge improvements in strength, physique hardness, and positive aggression while using this compound, an effect that can be at least partially attributed to the androgen-mimicking qualities of icariin. RPM promotes increased dopamine levels and decreased prolactin levels, both of which are triggers for increased testosterone.  Icariin can also enhance muscle contraction by decreasing the effects of acetylcholinesterase (AChE).  Acetylcholine (Ach) is a neurotransmitter necessary for muscle contraction, and AChE is responsible for disabling ACh at the neuromuscular junction.  Icariin blocks this disabling action, allowing for ACh to stay at the synapse and better exert its effects for a longer period of time- thus allowing for harder and stronger muscle contractions.
Icariin is a selective inhibitor of cyclic guanitric oxidesine monitric oxidephosphate (cGMP)- specific phosphodiasterase type 5 (PDE5 for the purpose of this article).  This is a notable characteristic, because PDE5 hydrolyzes cGMP  into an inactive molecule.  cGMP is important because nitric oxide requires cGMP to moderate vascular control and vasodilation.  So essentially, no cGMP; no vasodilation (the “PUMP”), because nitric oxide requires cGMP to work.  Conversely, the more cGMP; the more nitric oxide-induced vasodilation - therefore the greater the pumps. Icariin stops PDE5 from disabling cGMP and allows cGMP to extend its activity which increases the effects of nitric oxide in skeletal muscle and allows for a stronger muscle contraction and pump.  This is the same way a popular pharmaceutical product – Viagra® – works; which is essentially the most well-known PDE5 inhibitor on the market.
In scientific studies, pure icariin has been found to have roughly one-tenth the PDE5 inhibitory activity and nitric oxide productivity of Viagra®, and the dosage provided in RPM is tailored appropriately to provide similar effects.  In short, the PDE5 inhibition displayed by icariin puts RPM in a class above all other nitric oxide enhancers- as “pharmaceutical-strength” results are commonly experienced.
Oligomeric proanthocyanidins (OPCs) are essential components of RPM. OPCs have been shown in numerous studies to have the ability to block the conversion of androgens to estrogens (a process known as aromatizing). OPCs are a refined derivative of grape seed extract and exhibit qualities comparable to several widely marketed pharmaceutical aromatase inhibitors (i.e. Arimidex®). Compounds exhibiting aromatase inhibiting characteristics have been shown to reduce SHBG (steroid hormone binding globulin) as well.  This is important because this allows for a dramatic increase in free testosterone, which promotes longer, harder more intense workouts, rapid strength increases, greater protein synthesis, quicker recovery, and increased lipolysis (fat burning). This, coupled with the androgen-mimicking qualities of icariin, gives the product a unique “hardness” enhancing quality unlike anything else available. 
OPCs also protect against free radicals and subsequent DNA and oxidative damage, qualities that are extremely important to the hard-training athlete.  Oxidative damage is a common occurrence during stress and hard training, and it can have a halting effect on the subject’s gains in lean body mass.  Less oxidative damage leads to faster recovery which gives you the ability to train longer and harder.  
The nitric oxide-enhancing, vasodilatory properties of OPCs have been documented in countless studies.  The flavonitric oxideids contained in OPCs have been shown to increase levels of nitric oxide synthase, the enzyme that allows for the conversion of arginine to nitric oxide.  This is a critical element, because nitric oxide synthase competes with arginase for the utilization of the aminitric oxide acid L-arginine.  Arginase converts L-arginine into ornthine, and increased arginase and ornthine activity is counteractive to the nitric oxide production pathway.  Therefore, by increasing nitric oxide synthase, the flavonitric oxideids in OPCs “crowd out” arginase, allowing for more arginine to be processed into nitric oxide. The result is higher nitric oxide levels and even greater vasodilation, all of which additionally contribute to the unprecedented pumps and muscle hardness that subjects using RPM experience.
Naringin, and its novel component Naringenin, also contribute profound effects within the P-SARM Synthase AI complex.  Naringin (and Naringenin) exhibit remarkable anti-aromatase and estrogen-inhibiting properties by decreasing the cytochrome P450arom isoform, which is an enzyme that also allows for the oxidative metabolism for chemical modification and degradation of oral medications.  This can have very positive effects on the testosterone / estrogen ratio, and the combination of OPCs and naringenin act synergistically in reducing estrogen; allowing for more circulating free testosterone and all of its associated benefits.  Naringin and naringenin have also been shown to enhance the metabolism of caffeine and PDE5 inhibitors such as icariin, allowing for these compounds to be much more effective on a per dose basis - by up to 35%!!!
L-Arginine is the last component of the P-SARM Synthase AI matrix.  L-Arginine is an amino acid that is necessary for cell division, injury healing, ammonia displacement, hormone release, and immune function. Most importantly, L-arginine is necessary for the production of nitric oxide. As mentioned earlier, nitric oxide is derived from arginine and oxygen through a process called nitric oxide synthase, and exerts its effects on tissue through cGMP.  The inclusion of Arginine in the P-SARM Synthase AI complex allows for a steady, continuous supply of L-arginine for conversion to nitric oxide, allowing for a more effective product.  Numerous research studies document the positive effects of L-Arginine and nitric oxide on increasing lean body mass, and possibly even mediating greater growth hormone response.
Methyl-Xanthine Anhydrous Caffeine (MXAC) is the first component of the Methyl-AMP Complex and is a metabolic stimulant that heightens mental alertness and focus and improves muscle contraction and coordination.  MXAC also exerts very strong effects on vasodilation in a process that begins with the activation of norepinephrine and the deactivation of cAMP-PDE (the enzyme that breaks down cAMP). When MXAC acts on a cell, cAMP-PDE can no longer turn cAMP into AMP, so the action of cAMP is prolonged within the cell. When cAMP levels are increased, the blood vessels in skeletal muscle tend to relax and dilate. The result is more voluminous blood flow into the muscle, resulting in bulging vascularity and massive pumps.  MXAC also contains significant amounts of theobromine; another vasodilator that ups the amount of nutrients and oxygen into the brain and skeletal muscle.  This greater blood flow to the brain contributes to the cognitive enhancement capabilities of MXAC. By blocking adenitric oxidesine uptake without activating adenitric oxidesine receptors, MXAC triggers increased dopamine and serotonin levels which exerts a positive influence on mood and helps the subject maintain an improved state of mind and focus. 
Another added benefit of MXAC is the ability to stimulate the central nervous system, which helps users of RPM feel more alert - allowing for enhanced focus and clarity.   It also stimulates the neural system to fire muscles into action more effectively via norepinephrine stimulation and by producing changes in calcium activity; stimulating ion transport of potassium into non-contracting tissues. This is important because ion transport helps reduce the increase in blood potassium concentrations during exercise, helping maintain the excitability of the muscle fiber, allowing for a stronger, longer muscle contraction.
Chocamine , the other component of the Methyl-AMP Complex, is a specially standardized cocoa extract comprised of several different important constituents that enhance mood, cognitive awareness, and muscle contraction. PEA, tyramine, and L-tyrosine are the most prevalent constituents of chocamine, and have the biggest impact on the positive effects of the compound. The amino acid tyrosine has profound psycho-stimulant effects that improves cognitive function, as tyrosine is a precursor to the neurotransmitter dopamine. Tyrosine supplementation has been shown to increase dopamine and norepinephrine levels, which can be helpful for increasing athletic ability and cognitive function.  Tyrosine also has the ability to ward off exercise-related fatigue by creating a favorable dopamine / serotonin ratio, which can positively alter the subject’s state of mind and reduce mental fatigue.  This simple shift in the amino acid ratio can create a large difference in perception and concentration, and higher dopamine levels are closely correlated with increased focus and mood enhancement/anti-depressant activities.   Tyrosine has also been shown to reduce or prevent stress-related cognitive impairment, and has been attributed with mild suppression of glucocorticoid secretion.
Phenylethylalanine (PEA) and tyramine are two more important constituents of Chocamine.  PEA is a biogenic amine derived from the aminitric oxide acid phenylalanine, and it has some effects very similar to amphetamine.  It has strong mood-enhancing qualities, along with the ability to increase focus and offset lack of sleep.  Tyramine is another biogenic amine found in Chocamine, and is responsible for the increased release of NE in the neurons, creating an excitatory effect on the CNS.  It has also been shown to increase dopamine levels and increase the generation of cAMP, and also to aid in lipolysis. 
Summary
RPM is the first and only product that provides such a unique combination of performance and mood-enhancing effects. The benefits on RPM reach beyond high-performance workouts in the gym, but also promotes personal effectiveness and productivity in all aspects both mental and physical. Try some today!
Advised Use :
Take 1 dose approximately one hour before your workout. If you train in the evening, do not take within 6 or 7 hours of bedtime. If so, reduce you recommended dosage by 50%.
Dosage Chart :
Body Weight            Dose 
up to 65 kg          1 capsule pre workout
65 kg - 70 kg       2 capsules pre workout
70 kg - 80 kg       3 capsules pre workout
80 kg -100 kg      4 capsules pre workout
100 kg and up      5 capsules pre workout
Contents 110 Capsules